Isotretinoin is prescribed when acne has not improved with other treatments (like antibiotics, topical creams, or benzoyl peroxide) It works by:Greatly reducing oil (sebum) production in the skin Preventing clogged pores and reducing acne lesions (pimples, cysts, nodules) Often leading to long‑term remission or even a “cure” of acne after one course .It is not for mild acne, blackheads/whiteheads alone, or cosmetic use