Glutathione is a powerful natural antioxidant made in the body, and oral 500 mg tablets are commonly used for:Liver support – to help the liver detoxify the body, especially in conditions like fatty liver disease, hepatitis, or cirrhosis; some doctors recommend 500–1000 mg/day in such cases .Antioxidant effect – to reduce oxidative stress, which may help in conditions like diabetes, heart disease, and neurodegenerative disorders (though evidence is stronger for IV than oral use) Immunity support – to strengthen the immune system, especially when weakened by stress, infections, or chronic illnesses like chronic fatigue syndrome or HIV .Skin lightening – some people take 500 mg/day orally for several weeks to months to reduce melanin and lighten skin tone, based on studies showing modest skin-lightening effects .It is also sometimes used (along with other treatments) for conditions like Parkinson’s disease, Alzheimer’s, asthma, and to reduce side effects of chemotherapy, but in those cases IV glutathione is more common than tablets