Monobenzone cream (Monobenzone 20% w/w) is a topical depigmenting agent used mainly for:Permanent depigmentation in extensive vitiligo (more than 50% body surface area) Lightening normal skin around vitiligo patches to match depigmented areas Treating severe pigment disorders when repigmentation therapy fails It works by increasing melanin elimination from melanocytes, leading to gradual skin lightening